workshop

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Current Status and Future Developments of Databases on Alternative Methods

Annett Janusch, Margot D.O. van der Kamp, Krys Bottrill, Barbara Grune, David C. Anderson, Björn Ekwall, Michelle Howald, Roman Kolar, Hans J.D. Kuiper, Jean Larson, Gregorio Loprieno, Ursula G. Sauer, Adrian J. Smith and Jan B.F. van der Valk

This is the report of the twenty-fifth of a series of workshops organised by the European Centre for the Validation of Alternative Methods (ECVAM). ECVAM’s main goal, as defined in 1993 by its Scientific Advisory Committee, is to promote the scientific and regulatory acceptance of alternative methods which are of importance to the biosciences and which reduce, refine or replace the use of laboratory animals.
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2017-01-09T06:26:22+00:00 Tags: , , |

Genetically Engineered Cell Lines: Characterisation and Applications in Toxicity Testing

Friedrich J. Wiebel, Tommy B. Andersson, Daniel A. Casciano, Maurice Dickins, Volker Fischer, Hansruedi Glatt, Jean Horbach, Robert J. Langenbach, Walter Luyten, Gino Turchi and Alain Vandewalle

This is the report of the twenty-sixth of a series of workshops organised by the European Centre for the Validation of Alternative Methods (ECVAM). ECVAM’s main goal, as defined in 1993 by its Scientific Advisory Committee, is to promote the scientific and regulatory acceptance of alternative methods which are of importance to the biosciences and which reduce, refine or replace the use of laboratory animals.
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2017-01-09T06:26:27+00:00 Tags: , , |

Issues Relating to the Release of Proprietary Information and Data for Use in the Validation of Alternative Methods

Martin Todd, Bernward Garthoff, Wilfried Bernhardt, Gerd Bodé, Spencer Farr, Roman Kolar, Cyndy Lumley, Moniek Pieters, Vera Rogiers, Ursula Sauer, Horst Spielmann, Joseph Straus and Lars Warngard

This is the report of the twenty-seventh of a series of workshops organised by the European Centre for the Validation of Alternative Methods (ECVAM). ECVAM’s main goal, as defined in 1993 by its Scientific Advisory Committee, is to promote the scientific and regulatory acceptance of alternative methods which are of importance to the biosciences and which reduce, refine or replace the use of laboratory animals.
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2017-01-09T06:26:28+00:00 Tags: , , |

The Use of Transgenic Animals in the European Union

T. Ben Mepham, Robert D. Combes, Michael Balls, Ottavia Barbieri, Harry J. Blokhuis, Patrizia Costa, Robert E. Crilly, Tjard de Cock Buning, Véronique C. Delpire, Michael J. O’Hare, Louis-Marie Houdebine, Coen F. van Kreijl, Miriam van der Meer, Christoph A. Reinhardt, Eckhard Wolf and Anne-Marie van Zeller

This is the report of the twenty-eighth of a series of workshops organised by the European Centre for the Validation of Alternative Methods (ECVAM). ECVAM’s main goal, as defined in 1993 by its Scientific Advisory Committee, is to promote the scientific and regulatory acceptance of alternative methods which are of importance to the biosciences and which reduce, refine or replace the use of laboratory animals.
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2017-01-09T06:26:28+00:00 Tags: , , |

Reducing the Use of Laboratory Animals in Biomedical Research: Problems and Possible Solutions

Michael F.W. Festing, Vera Baumans, Robert D. Combes, Marlies Halder, Coenraad F.M. Hendriksen, Bryan R. Howard, David P. Lovell, Graham J. Moore, Philip Overend and Marie S. Wilson

This is the report of the twenty-ninth of a series of workshops organised by the European Centre for the Validation of Alternative Methods (ECVAM). ECVAM’s main goal, as defined in 1993 by its Scientific Advisory Committee, is to promote the scientific and regulatory acceptance of alternative methods which are of importance to the biosciences and which reduce, refine or replace the use of laboratory animals. One of the first priorities set by ECVAM was the implementation of procedures which would enable it to become well-informed about the state-of-the-art of non-animal test development and validation, and the potential for the possible incorporation of alternative tests into regulatory procedures.
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2017-01-09T06:26:42+00:00 Tags: , , |

Non-animal Tests for Evaluating the Toxicity of Solid Xenobiotics

Bice Fubini, Ann E. Aust, Robert E. Bolton, Paul J.A. Borm, Joachim Bruch, Gabriela Ciapetti, Ken Donaldson, Zoé Elias, Julie Gold, Marie Claude Jaurand, Agnes B. Kane, Dominique Lison and
Hartwig Muhle

This is the report of the thirtieth of a series of workshops organised by the European Centre for the Validation of Alternative Methods (ECVAM). ECVAM’s main goal, as defined in 1993 by its Scientific Advisory Committee, is to promote the scientific and regulatory acceptance of alternative methods which are of importance to the biosciences and which reduce, refine or replace the use of laboratory animals. One of the first priorities set by ECVAM was the implementation of procedures which would enable it to become well-informed about the state-of-the-art of non-animal test development and validation, and the potential for the possible incorporation of alternative tests into regulatory procedures.
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2017-01-09T06:26:46+00:00 Tags: , , |

Validation of Alternative Methods for the Potency Testing of Vaccines

Coenraad Hendriksen, Jean-Marc Spieser, Arnoud Akkermans, Michael Balls, Lukas Bruckner, Klaus Cussler, Arnold Daas, Johan Descamps, Roland Dobbelaer, Julia Fentem, Marlies Halder, Margot van der Kamp, Roger Lucken, Julie Milstien, Dorothea Sesardic, Donald Straughan and Antonio Valadares

This is the report of the thirty-first of a series of workshops organised by the European Centre for the Validation of Alternative Methods (ECVAM). ECVAM’s main goal, as defined in 1993 by its Scientific Advisory Committee, is to promote the scientific and regulatory acceptance of alternative methods which are of importance to the biosciences and which reduce, refine or replace the use of laboratory animals. One of the first priorities set by ECVAM was the implementation of procedures which would enable it to become well-informed about the state-of-the-art of non-animal test development and validation, and the potential for the possible incorporation of alternative tests into regulatory procedures. It was decided that this would be best achieved by the organisation of ECVAM workshops on specific topics, at which small groups of invited experts would review the current status of various types of in vitro tests and their potential uses, and make recommendations about the best ways forward (1).
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2017-01-09T06:26:48+00:00 Tags: , , |

The Availability of Human Tissue for Biomedical Research

Robert Anderson, Michael O’Hare, Michael Balls, Madeleine Brady, Diana Brahams, Avril Burt, Christophe Chesné, Robert Combes, Ashley Dennison, Bernward Garthoff, Gabrielle Hawksworth, Eric Kalter, Ann Lechat, David Mayer, Vera Rogiers, Dariusz Sladowski, Jacqueline Southee, Jacki Trafford, Jan van der Valk and Anne-Marie van Zeller

This is the report of the thirty-second of a series of workshops organised by the European Centre for the Validation of Alternative Methods (ECVAM). ECVAM’s main goal, as defined in 1993 by its Scientific Advisory Committee, is to promote the scientific and regulatory acceptance of alternative methods which are of importance to the biosciences and which reduce, refine or replace the use of laboratory animals. One of the first priorities set by ECVAM was the implementation of procedures which would enable it to become well-informed about the state-of-the art of non-animal test development and validation, and the potential for the possible incorporation of alternative tests into regulatory procedures.
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2017-01-09T06:26:48+00:00 Tags: , , |

Report on the COLIPA Workshop on Mechanisms of Eye Irritation1

Leon H. Bruner, Odile de Silva, Lesley K. Earl, Wolfgang Pape and Horst Spielmann

This report summarises the discussions of a workshop sponsored by the European Cosmetics, Toiletries and Perfumery Association (COLIPA). The workshop discussed the state-of-the-art of eye irritancy testing, and made recommendations as to the best ways in which to validate alternatives to the Draize eye irritation test. The importance of understanding the mechanisms of eye irritation, particularly when attempting to improve in vitro prediction of in vivo eye irritancy, was also emphasised.
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Alternatives to the Use of Animals in Higher Education

Jan van der Valk, David Dewhurst, Ian Hughes, Jeffrey Atkinson, Jonathan Balcombe, Hans Braun, Karin Gabrielson, Franz Gruber, Jeremy Miles, Jan Nab, Jason Nardi, Henk van Wilgenburg, Ursula Zinko and Joanne Zurlo

This is the report of the thirty-third of a series of workshops organised by the European Centre for the Validation of Alternative Methods (ECVAM). ECVAM’s main goal, as defined in 1993 by its Scientific Advisory Committee, is to promote the scientific and regulatory acceptance of alternative methods which are of importance to the biosciences and which reduce, refine or replace the use of laboratory animals.
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2017-01-09T06:26:50+00:00 Tags: , , |