toxicity

/Tag:toxicity

The Björn Ekwall Memorial Award 2015

Introduction by Ada Kolman & lecture text by Michael Balls

A personal, and therefore unavoidably biased, review is given, of the significance of the contributions made by selected Scandinavian individuals, organisations and events, to the development of in vitro toxicology procedures as potential replacements for toxicity tests in laboratory animals. In addition to their wider significance, these contributions had a profound effect on whatever contributions I have been able to make, myself. Nevertheless, while there has been much progress in the last 35 years or so, and many lessons have been learned, there is still much to be done, especially as animal tests remain entrenched as the preferred methods which set the gold standards and make regulators feel comfortable. Many of the clues to dealing with the questions and concerns which plague hazard prediction and risk assessment have long been available, but they have been ignored, largely for reasons which have little to do with the science of toxicology and the need to maintain the highest scientific standards. I have little doubt that Björn Ekwall, whose memory I feel privileged to honour, would have agreed with that last statement.
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Letters to the Editor

Various authors

The Use of Second Species in Toxicology Testing
A Response to the ABPI’s Letter to the Editor on the Use of Dogs in Predicting Drug Toxicity in Humans
The CPCSEA has urged the Drug Controller General of India to End the Use of Dogs in Regulatory Testing, in the Light of New Scientific Evidence
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