fetal bovine serum

/Tag:fetal bovine serum

Fetal Bovine Serum (FBS) — A Pain in the Dish?

Jan van der Valk and Gerhard Gstraunthaler

The use of Fetal Bovine Serum in replacement alternative methods is associated with serious animal welfare concerns, as well as worrying reproducibility issues

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The Use of Fetal Bovine Serum: Ethical or Scientific Problem?

Carlo E. A. Jochems, Jan B.F. van der Valk, Frans R. Stafleu and Vera Baumans

Fetal bovine serum (FBS) is a common component of animal cell culture media. It is harvested from bovine fetuses taken from pregnant cows during slaughter. FBS is commonly harvested by means of a cardiac puncture without any form of anaesthesia. Fetuses are probably exposed to pain and/or discomfort, so the current practice of fetal blood harvesting is inhumane. Apart from moral concerns, several scientific and technical problems exist with regard to the use of FBS in cell culture. Efforts should be made to reduce the use of FBS or, preferably, to replace it with synthetic alternatives.
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