ATLA Staff Writer

The results of the experimental prevalidation of three in vitro embryotoxicity tests from an ECVAM study are reported. The tests were: the rat whole embryo culture (WEC) assay; the micromass (MM) assay; and the embryonic stem cell test (EST). Three test chemicals, one assigned to each of the three classes of embryotoxicity (non-embryotoxic, moderately embryotoxic and strongly embryotoxic) and a positive and a negative control chemical were repeatedly tested in two laboratories on at least two separate occasions.
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