Pilar Prieto, Cecilia Clemedson, Annarita Meneguz, Walter Pfaller, Ursula G. Sauer and Carl Westmoreland

Chronic toxicity is a consequence of the persistent or progressively deteriorating dysfunction of cells, organs or multiple organ systems, resulting from long-term exposure to a chemical (1). Of relevance for cosmetic products are the oral, dermal and inhalation subacute (28-day) and subchronic (90-day) repeated dose studies conducted in rodents.
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